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Major adverse effects include hypoglycemia (dose-and timing-dependent, potentially life-threatening), hypokalemia, local injection-site reactions, lipodystrophy, and the rare development of anti-insulin antibodies leading to insulin resistance

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The best outcomes come when medication is combined with healthy eating, physical activity, strength training, good sleep, and ongoing medical supervision

However, my friend Rochelle, who has sensitive skin said she had rashes and skin irritation after using it and staying out under the sun

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