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Clemmons DR, Moses AC, McKay MJ, Sommer A, Rosen DM, Ruckle J
The activated Trem2 signal in stage 1 DAM facilitates transition to stage 2 DAM, which is characterized by an upregulation of lysosomal, phagocytic, and lipid metabolism pathway-related genes including cst7 and itgax
These findings suggest that FSP1 is a vitamin K reductase that maintains a warfarin-resistant non-canonical vitamin K cycle and inhibits ferroptosis by producing VK-H 2 via NADH consumption to prevent lipid peroxidation
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GFR stimulates the synthesis and release of endogenous growth hormone
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