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This means Ozempics weight-loss potential likely falls somewhere between these two trial results, though it remains lower than Mounjaro in equivalent-dose comparisons

The risk of hypoglycaemia would be more relevant if either agent were used alongside insulin or a sulfonylurea, or in the context of severe caloric restriction

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The well-documented disconnect between biomarker modulation and clinical outcomes in neurodegenerative diseases illustrated most starkly by the history of anti-amyloid therapies means that statistically significant reductions in p-tau or YKL-40 do not constitute evidence of meaningful clinical benefit

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