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Analyzing each patient's regime
It requires cofactors to function
In contrast, IM injections can be painful, and are more error-prone than injecting into fat
Length is individualized based on response and clinical progression
B12 injections are contraindicated for individuals with Lebers hereditary optic neuropathy, severe kidney disease, known cobalt or cobalamin allergy, and polycythemia vera
Endotoxin exposure can also contribute to the development of chronic diseases such as metabolic syndrome, diabetes, and cardiovascular disease
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