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Methods A systematic search was conducted across MEDLINE, Scopus, and Web of Science up to June 15, 2025, using PRISMA 2020 guidelines
For men 35 and over tracking fasting glucose, HbA1c, or insulin sensitivity as part of a broader recovery and performance protocol, the metabolic signal from MK-677 deserves real weight before use
Currently undergoing marketing approval procedures in China
Ahead, well unpack why interest is surging while carefully addressing the lack of FDA approval, limited human research, and growing regulatory scrutiny surrounding its use
H.GotesonA.GribbleF
Acta Diabetol 51(5):833843
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