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Methods Computer-aided molecular design, synthesis, and characterization All the computer-aided molecular design studies were performed in SZMAP/GamePlan 37 and vBrood 38 modules in OpenEye software and Molecular Operating Environment, MOE 39
Todos los textos referidos a nuestros productos de venta bajo prescripcin mdica se corresponden a los lineamientos aprobados por la Administracin Nacional de Medicamentos, Alimentos y Tecnologa Mdica (ANMAT)
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This D-retro-inverso configuration preserves the three-dimensional side-chain topology of the original FOXO4 sequence maintaining functional mimicry of the FOXO4 forkhead domains interaction surface with p53 while conferring exceptional proteolytic stability compared to the native L-amino acid sequence
