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11:15am - 12:30pm Metabolic Syndrome (Syndrome X) and Hypothyroidism Why most adults are overweight, Diagnosis, Testing, and Treatment Protocols for prescribing GLP-1 Agonists
doi:10.1007/s11096-024-01779-x Nauck MA, Mller TD
Cost and Accessibility Semaglutide (Wegovy) is FDA-approved for weight loss, while Ozempic (semaglutide 1 mg/2 mg) is approved for diabetes but often used off-label
This information is essential for accurate dosing
There is one exception: if Wegovy is prescribed for a covered indication other than weight loss (the drug has a separate FDA approval for cardiovascular risk reduction in adults with established cardiovascular disease and BMI 27), some Medicare plans may cover it under that indication
Physiological Relevance: Its still debated whether GLP-3 has significant independent biological activity or if its primarily a byproduct of proglucagon processing
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