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They are not recommended in pregnancy or breastfeeding, for those under 18, or with severe untreated medical conditions

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DSIP also modulates the hypothalamic-pituitary-adrenal (HPA) axis, which controls the release of stress hormones like cortisol and adrenocorticotropic hormone (ACTH)

One-way ANOVA was used to compare the mean values across multiple groups, followed by Dunnetts test for post hoc multiple comparisons to allowing for a detailed examination of significant differences between different experimental groups

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