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This is supported by clinical data across multiple study populations

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This change occurs both outside and inside

injected the nonmetabolizable glucose analogue 2-deoxy-D-glucose in the lateral ventricle to establish chronic low-energy metabolism models and reported that chronic suppression of brain energy metabolism, especially a reduction in glucose use, can induce epileptic seizures ( Antiseizure therapy causes changes in glucose metabolism

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However, it remains unlicensed by the MHRA and EMA for routine use in the UK, and access is currently limited to regulated research settings