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In the current study, depriving RPE cells of the essential GSH precursor Cys 2 by culturing cells in Cys 2 -free culture medium or blocking de novo synthesis of GSH by using GCL inhibitor BSO or blocking Cys 2 uptake by pharmaceutical inhibition of system x c caused cell death

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2025] Muller, D.R.P., Stenvers, D.J., Malekzadeh, A., Holleman, F., Painter, R.C., Siegelaar, S.E., 2023

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