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Tail vein samples were obtained for immediate glucose measurement as above, or into lithium heparin-coated microvette tubes for plasma insulin measurement using a mouse insulin-specific HTRF (Cisbio)

Severe Gastrointestinal Disease (e.g., Gastroparesis) Mounjaro may worsen symptoms or delay gastric emptying further in patients with preexisting motility disorders

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doi:10.1159/000499694

Going from 2 mg directly to 8 mg, or from 4 mg to 12 mg, dramatically increases the risk of severe gastrointestinal events and potential complications