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However, the researchers found that intracellular lipoxygenase levels were significantly increased

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( A - C ) 25 g/L/mouse IgG1 (n=5), 1 g/L/mouse mGIPR-Ab/P3 (n=6), 5 g/L/mouse mGIPR-Ab/P3 (n=6), 10 g/L/mouse mGIPR-Ab/P3 (n=6), or 25 g/L/mouse mGIPR-Ab/P3 (n=6)

10 In the DAPA-HF trial, among 4,700 patients with a significantly reduced mean LVEF (31% 6.7), most classified as New York Heart Association (NYHA) class II, dapagliflozin provided a 26% RR reduction in the primary composite outcome (CV death, HF hospitalisation and urgent visits for worsening HF), regardless of the presence or absence of type 2 diabetes (T2D), with a NNT of 21