The index event for the control group was defined as the first-time patients were eligible for inclusion of the study, based on diagnosis of MASLD/MASH, and no use of GLP-1 agonists after their diagnosis
Two years after stopping treatment, patients who had received higher doses had lower risks of death from any cause, as well as reduced risks of heart attack, stroke, cardiovascular-related death, heart failure, and heart valve problems
Still, specialists say awareness remains low
Side effects are usually mild at normal doses
Pietrocola et al., 2015)
Consistent with other GLP-1 receptor agonists administered through subcutaneous injections, the most frequently recorded adverse events of oral semaglutide treatment were nausea and vomiting