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Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart

Indeed, researchers found that obese individuals have higher levels of mast cell-derived tryptase.[ref][ref] Taking this one step further, some researchers link increased inflammation due to mast cell activation in adipose tissue to the cause of diabetes

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JAMA Health Forum

Joint aches, gut changes, fatigue, and mood swings are daily realities