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Tirzepatide , a dual GIP/GLP-1 receptor agonist, demonstrated superior efficacy to semaglutide in a landmark head-to-head trial, with patients receiving ZEPBOUND losing an average of 50 pounds over 72 weeks compared with 33 pounds among WEGOVY-treated patients

Clinical studies have also found a 200-fold increased risk of HCC in people with iron overload, such as HH patients

Severe side effects (persistent vomiting, inability to eat) are rare with proper dosing but should be reported to your provider immediately

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Endocrinology 161 , bqz046 (2020)

The company submitted Stelo for FDA approval