Short checklist before you buy - Does the label name the specific chemical form and dose per serving
While the nephroprotective effects of SGLT2i were initially derived from secondary endpoints of CV outcome trials (CVOTs), direct confirmation came from dedicated kidney focused trials: CREDENCE (Perkovic et al NEJM 2019| NephJC Summary), DAPA-CKD (Heerspink et al NEJM 2020| NephJC Summary) and finally EMPAKIDNEY (Herrington et al NEJM 2023| NephJC Summary)
However, neither HQ nor tretinoin should be used during pregnancy [38,39,40]
No, definitely not, Anjana said
Crucially, the researchers noted that participants had not yet reached a weight plateau when the study ended, suggesting the true long-term potential could be even higher
l-Citrulline protects from kidney damage in type 1 diabetic mice