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Carcinogenesis, Mutagenesis, Impairment of Fertility Long term studies in animals to evaluate carcinogenic potential have not been done

Since December 2025, many peptides have been classified as prescription medicines following a recommendation from Medsafes Medicine Classification Committee

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Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid beta-peptide-induced cholinergic dysfunction

It is used for weight loss in adults and pediatric patients ages 12 years and older with obesity, as well as adults who are overweight and have at least one weight-related risk factor, such as diabetes or high blood pressure

overall, the lifetime risk of ESKD is 1030% [2, 3]