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Patients should be reassured that gastrointestinal symptoms often improve with continued therapy as tolerance develops

In addition, a newer class of drugs called sodium-glucose cotransporter-2 (SGLT2) inhibitors demonstrated cardioprotective properties in trials with individuals who have diabetes and CKD, as well as people with CKD who do not have diabetes

LIXIPARK Study Group

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Nemmara, R

is supported by the National Institute of General Medical Sciences (NIGMS) grant P20GM109025, National Institute on Aging (NIA) grants R35AG71476 and R25AG083721-01, National Institute of Neurological Disorders and Stroke (NINDS) grant RO1NS139383, the Alzheimers Drug Discovery Foundation (ADDF), Ted and Maria Quirk Endowment, and Joy Chambers-Grundy Endowment