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Rodrguez-Meja UU et al
The fact that the double-cysteine mutations only partially abolish the physiological function may imply that not all the expressed mutants have an intact disulfide bridge and that the observed conformation is only one possible inactive state on the cell surface, as supported by the EM data and MD simulations below
Am J Physiol Lung Cell Mol Physiol 291 : L46L57 Hu S, Zhao H, Al-Humadi NH, Yin XJ, Ma JK 2006 Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway
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only considers bridged volume
