Such a strategy would aim to interrupt ferroptotic contagion rather than preventing its initiation
2.6 Analysis of oxidative stress SOD activity, glutathione (GSH) content, and malondialdehyde (MDA) levels (all of which are indicators of the oxidative stress burden) were measured in hepatic tissue homogenates using the colorimetric kits obtained from BioVision, Milpitas, CA, United States: SOD kit (Cat: K335100), GSH kit (Cat: K464100), and MDA kit (Cat: K739100), according to the guidelines provided by the manufacturer
Oxidative stress in nonalcoholic fatty liver disease: Pathogenesis and antioxidant therapies
These findings suggest that surface-modified MPs may contribute to vascular injury by disrupting the endothelial barrier and eliciting inflammatory responses
The cell wall is involved in adhesion, colonization, signal transduction and immune recognition, and plays an important role in the infection process because its dissolution leads to cell rupture and death
Role of Nrf2 in chronic liver disease