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The observed inconsistencies between available in planta, in vitro and in vivo (cell factory) data, however, led us to hypothesize that arGSTs might not (only) have the literature-proposed transport function but could play a central role in the biosynthetic step from leucoanthocyanidins ( 2 ) to anthocyanidins ( 3 )

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The RIPK1 inhibitor RIPA-56 significantly attenuates tubular epithelial cell necroptosis, reduces lipid deposition, and alleviates diabetic renal injury in STZ/HFD-treated db/db mice (84)

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doi:10.3233/JAD-160241 Hildebrandt W, Sauer R, Bonaterra G, Dugi KA, Edler L, Kinscherf R

A safer approach is to separate strong actives from GHK-Cu at first