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Research indexed on PubMed suggests DSIP has been studied in animal models in the contexts of response to stress, hormone modulation, and neuroprotection

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BPC-157 at $80120 monthly might reduce inflammatory cytokines and improve joint comfort through anti-inflammatory pathways, but you're extrapolating from tendon data with no OA-specific validation

2 Otoprotection in Zebrafish Lateral Line Hair Cells Uribe et al., Frontiers in Cellular Neuroscience (2015) This paper from the Coffin laboratory (with WSU co-authors) tested whether Dihexa could protect zebrafish lateral line hair cells (homologous to mammalian inner ear hair cells) from aminoglycoside-induced ototoxicity

At therapeutic doses, gut absorption becomes the limiting factor IV delivery removes that ceiling

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