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doi: 10.1371/journal.pmed.0030483

The main symptoms are usually the appearance of fatigue and tiredness, loss of muscle mass and various gastrointestinal problems

However, rates of these side effects are lower compared with other more common ones, like nausea, vomiting, and diarrhea

Patients are encouraged to report suspected side effects to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)

Researchers who understand GLP-1 injection techniques will find the process virtually identical for retatrutide, with the same emphasis on proper angle, depth, and rotation

Weight regain is common after stopping semaglutide, though not guaranteed