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This pattern of weight regain reflects the underlying pathophysiology of obesity as a chronic disease characterized by biological adaptations that defend against weight loss
This underscores the importance of tailoring the treatment to each individual
In the SUSTAIN trials, the majority of patients who reported nausea saw a reduction in symptoms within 4-8 weeks of starting treatment
they reduce the copay, not the drug's price
Only a fraction of the oral dose actually reaches systemic circulation
This makes it an appealing choice for individuals struggling with weight loss, especially when diet and exercise alone arent sufficient
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