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Many of the studies reviewed highlight promising behavioral, neurochemical, or microbiota-related effects of probiotic and prebiotic interventions, yet very few include direct measurements of oxidative-stress biomarkers

Elimination of senescent cells by treatment with navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain

Notably, ECs display considerably reduced levels of intercellular adhesion molecules (ICAMs) in comparison to ECs in peripheral organs, thereby imposing stringent limitations on immune cell ingress into the brain tissue [34, 35]

Conditioned media was collected from the PC cultures in the second day after the seedings and mixed in a 1:1 ratio with the medium of hEC [24]