Let vial sit for 2-3 minutes
The preclinical findings that there is no tolerance development toward the GLP-1R agonists tested and that the decline in drinking persists after treatment discontinuation suggest clinical applicability (Suchankova et al., 2015
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Anecdotally reported human side effects include nausea at higher doses (more common with capsules), dizziness, and transient injection site reactions
Similarly, trials of tirzepatide have shown substantial weight loss with a comparable proportion of lean mass reduction
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