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Studies typically begin with a low titration phase to allow receptor adaptation (e.g., 2mg or 4mg weekly), increasing slowly over months to reach the target maintenance dose (up to 12mg in some trials, though this product contains 20mg total)
(2006) Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization Peptides, 27(4):921-930
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Distribution is limited to UK and European research territories
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