glp-1 drugs and autoimmune disease Can Boost Immunity? GLP-1 Agonists in Autoimmune Disease

References Schett G, McInnes IB, Neurath MF

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While also not prescribing GLP-1s personally, Brandon Peters, MD, FAASM, a sleep physician at Virginia Mason Medical Center, has patients taking GLP-1s for obesity or diabetes and seeing improvements in their OSA

NICE NG28 recommends prioritising SGLT-2 inhibitors in people with established atherosclerotic cardiovascular disease, heart failure, or chronic kidney disease often alongside or instead of metformin due to these organ-protective effects [10] [8] GLP-1 receptor agonists (e.g., semaglutide, liraglutide) generally produce greater HbA1c reductions (1.01.5%) and significant weight loss, but are injectable and more costly

Medical supervision is essential because peptides influence hormonal and metabolic pathways that require monitoring

However, the known contraindications that clinicians must observe include personal or family history of medullary thyroid carcinoma and multiple endocrine neoplasia syndrome type 2 (MEN 2), both related to thyroid C-cell concerns identified in rodent studies