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showed that ARID1A-deficient cancer cells expressed low levels of the key cystine transporter SLC7A11 and thus exhibited low basal levels of GSH, which made these cancer cells specifically vulnerable to inhibition of the GSH metabolic pathway 25
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They are particularly useful for addressing B12 deficiencies
Interestingly, concurrent same-day colonoscopy was identified as a protective factor, with a lower risk of food retention (OR 0.18, p -value = 0.003) in patients undergoing both EGD and colonoscopy [29]
In vivo, GLP-1 has a half-life of only 23 min, preventing its therapeutic utilisation 31,32,33,34,35