Bioequivalence Analysis For EMA bioequivalence analysis, co-primary endpoints were log-transformed and analysed separately using an analysis of variance (ANOVA) model with treatment (2G oral semaglutide or 1G oral semaglutide), period (PK-sampling visits), sequence (starting with 2G oral semaglutide or 1G oral semaglutide) and participant nested within sequence as fixed effects
Vitamin b12 and long acting hydroxocobalamin has been reported too be required for normal blood formation and for treating anemias
Fan KJ, Wu J, Wang QS, Xu BX, Zhao FT, Wang TY
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Inclusion & Exclusion Criteria