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For people with no neurological involvement Initially administer hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks, then administer hydroxocobalamin 1 mg intramuscularly every 23 months for life
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5,11 This realization has prompted molecular studies of NADPH metabolism and its exploitation for the development of anticancer agents
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Research into predictive biomarkers could improve patient selection and treatment monitoring
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