Although EMPEROR-R enrolled patients with and without type 2 diabetes, the primary outcome of the trial (a composite of CV death and hospitalization for HF) was almost identical in both groups, suggesting that the different population didnt affect the results, at least for the primary outcome
That can feel like freedom
The information below was written before the recent research, but the advice remains the same
It is important to maintain open communication with your healthcare team about any side effects or concerns during GLP-1 treatment
Key reasons GLP-1s require heightened caution in eating disorder populations include: Appetite suppression that may reinforce restrictive behaviors Rapid or significant weight changes that can increase psychological distress Heightened focus on food intake, body cues, or weight-related outcomes Temporary behavioral changes that may mask symptoms rather than address underlying drivers Eating disorders are multifaceted mental health conditions that cannot be effectively treated through appetite or weight changes alone
The Harding lab animal studies used various doses, often extrapolated by community members using simple body weight scaling