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This also needs to be validated in more rigorous study designs. Two of the women reported feeling much better after lowering their dosage, though one woman required an add-on treatment of bupropion, an antidepressant known to help with anhedonia by boosting dopamine levels

Although these agents lack the toxicities of conventional, cytotoxic chemotherapy agents, they are not without their side effects, termed immune-related adverse events (irAEs)

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Some people take one, some people take the other, and some take both