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Some of these effects are in fact analogous to those previously observed by reducing beta cell/islet cholesterol with simvastatin: for example, both manipulations led to a reduction in GLP-1R plasma membrane lateral diffusion under vehicle conditions, as well as acute increases in GLP-1R-induced cAMP and islet insulin secretion responses
doi:10.1016/j.disamonth.2021.101287
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It has also been reported that GLP-1RAs may have cardiovascular protective effects among individuals with type 2 diabetes, and they therefore provide an attractive therapy option for patients with NAFLD [14]
Not, not an exacerbation of POTS, just that, you know, let's say her baseline, her rate is 60 and maybe it was 65
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