Patient 4 76-year-old woman who had a deep microneedling treatment around mouth
Nat Cell Biol 10:147783
5 mg vial + 2 mL BAC water: Concentration = 2,500 mcg/mL 250 mcg dose = 10 units (0.1 mL) on a 100-unit insulin syringe 500 mcg dose = 20 units (0.2 mL) on a 100-unit insulin syringe Doses per vial: 20 doses at 250 mcg, or 10 doses at 500 mcg Supplies Needed (8-Week Cycle at 250 mcg/day) 3 vials BPC-157 (5 mg each) provides 60 doses, covers 56 days with margin 3 vials bacteriostatic water (30 mL each) 60 insulin syringes (2931 gauge, 100-unit) Alcohol prep pads Administration Injection Technique BPC-157 goes subcutaneous (SubQ)
Liposomal glutathione is designed to mimic this efficiency in an oral format by using a phospholipid bilayer to protect the glutathione from stomach acid, making it a more convenient and cost-effective daily alternative.
Among surviving patients, the most severely affected patients have intellectual disability, with IQs ranging from the low 50s to around 60, progressive cerebellar disease and ataxia, recurrent bacterial infections, chronic metabolic acidosis, and hemolytic anemia
The length of the study whether short-term or long-term also affects cumulative dosing and helps manage potential toxicity risks