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Therefore, ATF4-mediated upregulation of SHMT2 contributes to a higher level of dTTP in T315I-Bcr-Abl-32D cells
Ahi ZB, Arican F, Sancakli A
In addition, berberine is small in size, so it can available through the blood-brain barrier and effectually act on molecular target, showing great therapeutic potential in the treatment of neurodegenerative diseases (Wang et al., 2005
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This can lead to cell damage, inflammation, and a higher risk of diseases like heart problems and brain disorders
It has been proposed that a reduced GST activity in these individuals would slow the rate of excretion of isothiocyanates, thereby increasing tissue exposure to isothiocyanates after cruciferous vegetable consumption (55)
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