Safety evaluation of AOD9604, a synthetic peptide for use in obesity
By inhibiting this enzyme, 5-Amino-1MQ prevents the loss of these precursors, effectively redirecting them into the NAD+ salvage pathway
Circumference Measurements: Weekly measurements of waist, hips, thighs, and arms using consistent technique (same time of day, same measurement points) track regional changes that correlate with fat loss
Biomed Res Int
Researchers continue to investigate how NNMT inhibition affects intracellular signaling, energy utilization, and the complex biochemical pathways involved in maintaining cellular homeostasis
The compound inhibits the NNMT enzyme in fat cells, which increases cellular NAD+ levels and shifts adipocyte metabolism from fat storage to fat burning