Triple-agonists are a newer type of medication that binds to and activates three distinct receptor types simultaneouslythe goal is to achieve a stronger effect
Recent research suggests GLP-1 therapy may help
STEP 5: sustained 15.2% at 104 weeks [2]
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Ideally, we should offer three evidence-based pathways: OM, bariatric surgery, and combination therapy
Additional safety concerns include hypoglycemia risk when used with insulin or insulin secretagogues, potential acute kidney injury with dehydration, and with semaglutide, worsening of diabetic retinopathy in patients with pre-existing retinopathy