The combination is contraindicated in pregnancy due to teratogenic risks, particularly the association between topiramate and orofacial clefts
Mannucci E, Caiulo C, Naletto L, Madama G, Monami M (2021) Efficacy and safety of different basal and prandial insulin analogues for the treatment of type 2 diabetes: a network meta-analysis of randomized controlled trials
Initial weight loss typically begins within the first 4-8 weeks, with most patients losing 2-4% of body weight monthly during active loss phases
The combination may intensify these symptoms, potentially leading to dehydration, electrolyte imbalances, or treatment discontinuation
m bo sc khe v tng cng hiu qu th vic hiu r thuc b no Ginkgo Biloba ny ung my vin? l iu v cng quan trng
This weight loss is attributed to its ability to reduce appetite and delay gastric emptying