Lower insulin requirements are also noted in real-world studies ( 4.2.2 RCTs In RCTs, insulin dose reductions were observed with the addition of GLP-1RA (61) ( Table 1 )
however, GLP-1 receptor agonists and SGLT2 inhibitors are more strongly recommended over DPP-4 inhibitors
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Albulushi A, Tanoh DB, Almustafa A et al (2024) Comparative effects of glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors on heart failure with preserved ejection fraction in diabetic patients: a meta-analysis
The most elaborate theoretical protocol means nothing if you cannot execute it consistently