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Moreover, supplementation with Lactobacillus plantarum (DP189) and GOS restored gut microbial composition, improved gut and BBB integrity, reduced cortical inflammation and elevated acetylcholinesterase activity, reversing anxiety and depression-like behaviors in mice (Wang J
doi: 10.1016/bs.apoc.2020.08.002 208 VisscherKMGeerkeDP
That steadiness supports more predictable appetite suppression and blood sugar regulation
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When the hypothalamic-pituitary-adrenal axis becomes dysregulated, cortisol levels spike and stay elevated
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