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Although, the present study did not provide evidence for the involvement of Epac in OA- mediated PI hydrolysis, demonstration of Epac2 expression in STC-1 cells and published reports in other cell types support our conclusion about the role of Epac/PLC- pathway in Ca 2+ mobilization
doi: 10.3389/fmed.2025.1462145 Received 09 July 2024 Accepted 14 March 2025 Published 26 March 2025 Volume 12 - 2025 Edited by Juan Carlos Mayo, University of Oviedo, Spain Reviewed by Pedro Gonzalez-Menendez, University of Oviedo, Spain Yao Luo, Sichuan University, China Zilong Zhao, University of Texas MD Anderson Cancer Center, United States Updates Copyright 2025 Li, Deng, Jiang, Shi, Xu and Liu
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