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Relevant CYP3A4 substrates include statins like atorvastatin and simvastatin, calcium channel blockers, certain anticoagulants including apixaban and rivaroxaban, immunosuppressants like cyclosporine, and a wide range of other compounds

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Niitsu Y, Sato Y, Takanashi K et al (2020) A CRAF/glutathione-S-transferase P1 complex sustains autocrine growth of cancers with KRAS and BRAF mutations

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