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FDAs March 11 enforcement report listed Jixianglong recalls of semaglutide, for Rx compounding use only. The report attributed the recalls to failing to complete process validation and bacterial endotoxin method validation before distribution.
We assessed the GLP-1R agonists (exenatide, liraglutide, dulaglutide, semaglutide) and the dual GIPR/GLP-1R co-agonist tirzepatide as separate classes
For a comparison of what to look for when evaluating polyphenol content, the buying guide and 2025 analysis are useful starting points
Define success metrics: Establish clear parameters for adequate response (e.g., referencing manufacturer-approved response benchmarks from the approved products prescribing information) and criteria for continuing or discontinuing therapy
Most protocols run 4 weeks, with reassessment at the 4-week mark to evaluate symptom response and adjust future dosing if needed
Peptide therapy should only be used under medical supervision
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