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It slows the rate at which food moves from the stomach into the small intestine, creating prolonged feelings of fullness after smaller meals
Nature 580 , 9399 (2020)
Delayed gastric emptying is one of the mechanisms by which semaglutide promotes a feeling of fullness and reduces food intake
As part of the incretin system, GLP-1 helps stabilize post-meal glucose levels by enhancing insulin secretion, suppressing glucagon release, slowing gastric emptying, and increasing feelings of satiety (5)
For patients with type 2 diabetes or prediabetes, this dual benefit of weight loss and glycemic control is particularly advantageous
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