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486,487,488 Notably, filgotinib has good oral availability, reaching maximum plasma concentrations at 13 h and plasma steady-state concentrations on day 2, making it a promising biologic agent for the treatment of UC

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Mm-hmm (affirmative)

This can cause problems like fatigue, hair loss, or muscle weakness

Jumping back in at a maintenance dose after a long break can cause severe nausea and vomiting

[10] This supports a role for an NPY-related pathway in that animal model