Pre-existing oxidative stress creates a docking-ready conformation of the SARS-CoV-2 receptor-binding domain
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The receptor question is itself contentious: integrin V5 has been proposed as a functional receptor mediating irisin effects on bone and adipose tissue, and V3 integrin has been implicated in neuroprotective effects, yet neither has been universally accepted as a bona fide irisin receptor, and the binding affinities reported vary across experimental systems (Kim et al., 2018
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Fetal lactate, cortisol, and norepinephrine concentrations, and blood gas measures were similar between groups (Table 3)