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Collectively, they presented a multi-year, multi-hundred-million-dollar litigation burden for any biosimilar developer willing to fight through all of them simultaneously

The result is reduced potency and inconsistent dosing

Discontinuation rates from the phase 2 trial due to side effects were generally low, though the broader literature on GLP-1 receptor agonists notes that discontinuation rates across the class can reach 20-50% within the first year

Unlike oral supplements, injections deliver the nutrient straight into your bloodstream, allowing for faster absorption and better effectiveness

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Among the late responders, 30% eventually lost at least 15% of their starting weight