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restrictive + malabsorptive Duodenal switch with biliopancreatic diversion (43845): Highest weight loss (~40% EBWL)

This study shows that -MSH is expressed in the heart and it protects against pathological cardiac remodeling by activating MC5-R in cardiomyocytes

Zepbound is FDA-approved for weight loss

12 In high concentrations, GLP-1RAs show lipolytic activity

It slows intestinal motility and increases water reabsorption in the colon

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