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Patients with existing cardiovascular disease actually experienced cardiovascular benefits (reduced heart attacks and strokes) despite temporary heart rate elevation, suggesting the overall metabolic effects of weight loss outweigh concerns about transient rate changes
The risk is severe caloric restriction that drops below 800 to 1,000 calories per day, which triggers metabolic adaptation, muscle loss, nutrient deficiencies, and hormonal disruption
A frequent speaker at corporations, he has been a TEDx speaker, a Singularity University speaker and guest at numerous interviews for radio and podcasts
The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism
J Am Coll Cardiol 2025;85:1721-35
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